This issue of Otolaryngologic Clinics, Guest Edited by Drs. Adam I. Levine, Samuel Demaria Jr., and Satish Govindaraj, focuses on Anesthesia in Otolaryngology. Articles in this issue include: Perioperative Guidelines in Anesthesia; Simulation and Education in Anesthesia; Patient Safety in Anesthesia; Anesthesia and Head and Neck Trauma; Anesthesia in Diagnostic and Therapeutic Pediatric Bronchoscopy; Anesthesia in Diagnostic and Therapeutic Adult Bronchoscopy; Regional Anesthesia and Acute Pain Management; Anesthesia and Chronic Pain Management; Anesthesia and Enhanced Recovery After Head and Neck Surgery; The Difficult Airway and Anesthesia; Anesthesia and Management of the Narrow Airway; Neuro-otology and Anesthesia; Anesthesia in Critical and Postoperative Care Management; and Anesthesia for Ambulatory and Office-based ENT Surgery.