In this issue of Rheumatic Disease Clinics, guest editor Dr. Kristine A. Kuhn brings her considerable expertise to the topic of Microbiome and Rheumatic Diseases. Top experts explore key topics related to the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathogenesis of rheumatic diseases. Topics include upper respiratory microbiome in vasculitis; intestinal microbiome in scleroderma; intestinal microbiome in lupus; and more. Contains 11 relevant, practice-oriented topics including GI microbiome in RA and medication metabolism; animal models informing the role of the microbiome and its metabolites in RA; juvenile rheumatoid arthritis; microbiome in axSpA; gout; and more Provides in-depth clinical reviews on microbiome and rheumatic diseases, offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews