This issue of Neurosurgery Clinics, guest edited by Dr. Nathaniel P. Brooks and Dr. Michael Y. Wang, is devoted to New Technologies in Spine Surgery. Articles in this issue include: Endoscopic Lumbar Discectomy, Endoscopic Cervical Foraminotomy, Endoscopic Lumbar Interbody Fusion, Endoscopic Lumbar Decompression, Lateral Lumbar Interbody Fusion, Retropleural Thoracic Approach, Novel Intervertebral Technologies, Surface Technologies for Fusion, Cell derived/Stem Cell Technologies for Fusion, Disk Replacement, Enhanced Recovery in Spine Surgery/Perioperative pain management, Imaging Technologies, Robotic Instrumentation Placement, Minimally Invasive Deformity Advances, Tissue Engineering/Regenerative Treatments, Minimally Invasive Tumor Ablation, and more.