These four volumes, originally published between 1973 and 1988, were intended to provide a broad survey of cognitive neuroscience, a field known variously as physiological psychology or psychobiology in the 1970s and 1980s when the books were written. The general goal was to summarize what was known about the relation between brain and mind at that time, with an emphasis on sensory and perceptual topics. Out of print for many years, the Tetralogy is now available again, as a set for the first time (which is as the author envisaged it), or as individual volumes.

William R. Uttal was Professor Emeritus of Psychology at the University of Michigan and Professor Emeritus of Engineering at the Arizona State University. Uttal was a prolific author whose output included 30 books and 140 scientific articles.