Crop Protection, Volume 55, the latest release in the Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters on RNAi Plus, where microbes enhance RNAi: Mechanism and Applications, Symbionts in whiteflies, miRNAs from the microbiome as drivers in the insect, a critical view on insect microbiome data analysis and interpretation, Insect-microbe interactions and transmission as shaped by future climate changes, Intestinal bacteria of the German cockroach and its interaction with entomopathogenic fungus, and Beyond Baculovirus: Alternative biotechnological platforms and pest control based on insect viruses.