In this issue of Otolaryngologic Clinics, guest editors Drs. Amy Y. Chen and Michael C. Singer bring their considerable expertise to the topic of Thyroid and Parathyroid Disease. Top experts in the field discuss key topics such as avoiding complications of thyroidectomy: preservation of parathyroid glands; RLN monitoring; RFA for benign nodules and for cancer, too; surgery for secondary hyperparathyroidism; autofluorescence of parathyroid glands; and more. Contains 15 relevant, practice-oriented topics including surgical management of substernal thyroids; avoiding complications of thyroidectomy: RLN and SLN preservation; recognizing and managing 4-gland hyperplasia; pearls to find hard-to-identify parathyroid glands; future directions; and more. Provides in-depth clinical reviews on thyroid and parathyroid disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.