The Lethal Protector renews rivalries with the Amazing Spider-Man! Eddie Brock and his alien symbiote return to torment Peter Parker - and they're deadlier than ever! But Venom makes dangerous new enemies when he crosses the Sinister Six! As the world darkens for Eddie, the symbiote begins to hunger - and target the innocents Venom used to protect! To face his most nightmarish foe, Spidey must turn to the Fantastic Four for help - and not for the first time! But a fateful decision could forever change things for Peter and Eddie! Plus: Nova the Human Rocket hurtles into Venom's path! Collecting: Peter Parker: Spider-Man (1999) #9-10, 16-17; Nova (1999) #7; Amazing Spider-Man (1999) #19; Spectacular Spider-Man (2003) #1-5; Spider-Man/Fantastic Four (2010) #2; material from Amazing Spider-Man (1999) #12, Peter Parker: Spider-Man (1999) #12, Spider-Man Family (2007) #1-2