Unveiling the hidden connections in the network of knowledgeHermes II: Interference is the second in a series of works by philosopher Michel Serres using Hermes, god of communication, as an archetypal symbolic figure for reflecting on philosophy and the arts and sciences. Serres delves into the concept of interreferentiality, proposing that every node-whether it be knowledge, objects, or people-exists within a network where it both receives and transmits information. He argues against the existence of a dominant center or pole within these networks, emphasizing that each node can temporarily serve as a focal point depending on context. Serres presents unique insights into topics such as the nature of knowledge, the world of objects, intersubjectivity, the origins of geometry, the interplay of music and background noise, and empiricism. By identifying parallel structures across these areas, Serres unifies them into a comprehensive theoretical framework, revealing hidden connections and potential future influences. Additionally, this work includes a critique of Gaston Bachelard’s The Formation of the Scientific Mind and concludes with an analysis of communication in HergÉ’s The Castafiore Emerald. Hermes II is a unique blend of ancient and modern perspectives, combining rigorous analysis with an optimistic outlook and highlighting the interconnectedness of knowledge and its implications for fostering peaceful relations within the network of life.